Disease: Childhood Acute Lymphoblastic Leukemia
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
YY1 P25490 YY1 transcription factor Transcription factor 0.99 0.481 0.808
XRCC5 P13010 X-ray repair cross complementing 5 Enzyme 1.00 0.554 0.808
XRCC1 P18887 X-ray repair cross complementing 1 6.3E-09 0.421 0.923
VEGFA P15692 vascular endothelial growth factor A Signaling 2.4E-05 0.266 0.923
TYMS P04818 thymidylate synthetase Enzyme 0.72 0.425 0.846
TRG T cell receptor gamma locus 0.631 0.538
TRBV20OR9-2 T cell receptor beta variable 20/OR9-2 (non-functional) 0.403 0.923
TRB P0DSE2 T cell receptor beta locus 0.636 0.538
TP53BP1 Q12888 tumor protein p53 binding protein 1 Epigenetic regulator 1.00 0.520 0.731
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
TOP2A P11388 DNA topoisomerase II alpha 0.99 0.497 0.731
TNFSF10 P50591 TNF superfamily member 10 Signaling 0.13 0.413 0.885
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962
TGFB1 P01137 transforming growth factor beta 1 Signaling 3.7E-02 0.287 0.962
TG P01266 thyroglobulin Enzyme modulator 2.9E-59 0.480 0.808
TFRC P02786 transferrin receptor Enzyme 7.0E-05 0.437 0.885
TERT O14746 telomerase reverse transcriptase Enzyme 0.99 0.374 0.846
TERF1 P54274 telomeric repeat binding factor 1 0.91 0.563 0.692
TERC telomerase RNA component 0.471 0.846
TCL1B O95988 T cell leukemia/lymphoma 1B 1.0E-02 0.561 0.500
TCL1A P56279 T cell leukemia/lymphoma 1A 5.7E-10 0.558 0.500
STAT5B P51692 signal transducer and activator of transcription 5B Nucleic acid binding 1.00 0.442 0.808
STAT3 P40763 signal transducer and activator of transcription 3 Nucleic acid binding 1.00 0.320 0.923
SOAT1 P35610 sterol O-acyltransferase 1 Enzyme 7.4E-10 0.424 0.846
SNAP25 P60880 synaptosome associated protein 25 Transporter 0.99 0.489 0.808